2Erzurum Regional Training and Research Hospital, Cardiology, Erzurum, Turkey
3Heart Center, Ataturk University Medical School, Cardiology, Erzurum, Turkey
4Hisar Intercontinental Hospital, Cardiology, Ä°stanbul, Turkey DOI : 10.31086/tjgeri.2021.228 Objectives: Although renal insufficiency is associated with high mortality in patients with acute coronary syndrome, studies have often excluded patients of advanced age who have renal insufficiency. The present study aimed to determine the relationship between renal insufficiency and mortality predictors in patients with non-ST-segment elevation myocardial infarction (NSTEMI) who were aged 65 and older.
Methods: The study included 537 NSTEMI patients aged 65 years and over, who were followed up for at least 12 months, who were admitted to the hospital with the diagnosis of NSTEMI and underwent coronary angiography. Sociodemographic and clinical features, laboratory parameters, and clinical evaluation variables were recorded at the time of admission. The patients were divided into four groups according to their ages and creatinine clearance values.
Results: The mean age of the patients was 76.17 ± 6.64 years, and 256 (47.7%) of them were women. According to the applied multivariate age-stratified Cox regression analysis, independent predictors of one-year mortality were found to be creatinine clearance (p=0.005), left ventricular ejection fraction (p<0.001), and coronary revascularization (p=0.004).
Conclusion: Creatinine clearance, left ventricular ejection fraction, and coronary revascularization are robust and independent predictors of one-year mortality in NSTEMI patients.
Keywords : Non-ST Elevated Myocardial Infarction; Renal Insufficiency; Mortality; Acute Coronary Syndrome